Diagnostic Accuracy of Body Mass Index and Fasting Glucose for The Prediction of Gestational Diabetes Mellitus after Assisted Reproductive Technology

Authors

  • Arezoo Arabipoor Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
  • Ashraf Moini Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
  • Azam kouhkan Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran, Postal address: Number 12, East Hafez Avenue, Bani Hashem Street, Res
  • Hamid Reza Baradaran Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran
  • Mohammad Ebrahim Khamseh Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran
  • Reihaneh Pirjani Department of Gynecology and Obstetrics, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Roya Hosseini Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
  • Zahra Zolfaghari Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Abstract:

Objective Background: To determine maternal pre-pregnancy body mass index (BMI), first trimester fasting blood sugar (FBS) and the combination (BMI+FBS) cut-points for at risk pregnant women conceived by assisted reproduction technology (ART) to better prediction of infertile women’s risk of developing gestational diabetes mellitus (GDM). MaterialsAndMethods In this nested case-control study, 270 singleton pregnant women consisted of 135 (GDM) and 135 (non-GDM) who conceived undergoing ART were assessed. GDM was confirmed by a one-step glucose tolerance test (O-GTT) using 75 g oral glucose. BMI was classified base on world health organization (WHO) criteria. Relationship between BMI, FBS and BMI+FBS with the risk of GDM development was determined by logistic regression and adjusted for confounding factors. ROC curve analysis was performed to assess the value of BMI, FBS and BMI+FBS as prediction of GDM. P

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volume 13  issue 1

pages  32- 37

publication date 2019-06-01

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